Salary Details: Grade 6, £33,518 per annum
Allowances: plus £2,923 London Allowance
Contract Type: Temporary/Fixed term
Contract Term: Full time
A 3-year World Wide Cancer Research-funded Research Associate position is available in the laboratory of Pierre Guermonprez in the Peter Gorer Department of Immunobiology, at King’s College London. Checkpoint blockade immunotherapies successfully unleash the potential of pre-existing T cell responses against tumor antigens. However, the very development of such T cell responses is constrained by the paucity and functional impairment of conventional dendritic cells (cDCs) the tumor micro-environment. In this context, adoptive transfer of antigen-loaded cDCs might prove synergistic with immune checkpoint blockade. However, this prospect is limited by the current cDCs culture system which are poorly amenable to immunotherapy.
The project aims at developing a new method to generate human dendritic cells amenable to cancer immunotherapy.
More information to apply here : PostDoc Cancer Immunology Kings College London